Do you have a garage? If so, then why not just insulate it and/or use a heater to maintain higher ambient temps.
If you park your car outside, some simple adjustments include using "hotter" plugs or increase their gap closer to the manufacturer's maximum, raising fuel pressure (see more below), perhaps a leaner AFR, etc.
If none of the above will do, then can you detail the extent to which your concern about "drop out" applies to our EFI cars (with stock ECU or DSMLink)? Is the concern specific to how cold temps affect:
1) injector flow/spray capabilities? I am not sure that the effect, if any, is substantial, especially when the fuel pump and injectors have been upgraded;
2) TB/intake flow? With the ECU or DSMLink's ability to adjust timing and fuel relative to the amount of air the MAS sees, the level of knock detected, etc., is low temp, air flow velocity at start up really that much of a concern? Velocity becomes more of a a factor when you get going, particularly when trying to make more power or achieve greater response
3) e85 fuel freezing? Likely not a concern considering the properties of the ethanol and gas in the mixture.
4) vaporization or fuel volatility? Now this IS an issue. Ethanol has a flash point of ~55 deg F (12.7 deg C), so below that it will does not produce a flammable fuel air mixture. The 15% gas in e85 helps to address this issue. At even colder temps, adding more gas (1-2 gallons per tank of e85) should do the trick.
Other cold start concerns could perhaps be addressed by using the appropriate grade of oil, a high CCA battery, and as someone suggested a block heater. Otherwise, make it a movie on demand night ;-)