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NLTS itself is not hard on a transmission. You can NLTS without lifting and without any aid with a good shifting transmission, and that is hard on a tranny.
NLTS does you a favor by cutting power to your preset RPM so you can make those relaxed shifts, normal speed shifts, etc, and keeping the turbo spooled.
Back when I was racing my dads Mustang, I would NLTS that car all day without any aids. If I missed a gear, the motor would redline. With some sort of aid (such as ECMLink NLTS), it would have just bounced off the rev limiter, whatever it would have been set at.
I had NLTS in my Mazdaspeed3 as well. It was nice to be able to run consistently without having to kill my transmission. I was able to keep my foot planted, but spark was cut so the clutch wasn't being engaged at a ridiculously high RPM.